Diagnosis of Surgical Site Infection

Journal of Clinical Orthopaedics | Vol 4 | Issue 2 |  July-Dec 2019 | page:12-16 | Dr. Manish Kothari


Author: Dr. Manish Kothari [1]

[1] Consultant Spine Surgeon, Jaslok Hospital & Research Centre, Mumbai

Address of Correspondence
Dr. Manish Kothari
Jaslok Hospital & Research Centre, Mumbai
E-mail: dr.manish.kothari@jaslokhospital.net


Abstract

Diagnosis of Surgical site infection is one of the most important factors that determines the further management of SSI. The diagnosis is based on various factors including clinical, laboratory investigations, Radiology, Bacteriology and molecular modalities. The current review summarises the salient features in all modalities.
Keywords: Surgical Site infection, Diagnosis.


References

1. Harrop JS, Styliaras JC, Ooi JC, Radcliff KE, Vaccaro AR, Wu C. Contributing factors to surgical site infections. J Am Acad Ortho Surg. 2012; 20(2):94-101.
2. WHO document on Global Guidelines For the Prevention of Surgical Site Infection. WHO Guidelines Development Group; Geneva, Switzerland; 2016;58-177
3. Guideline for Prevention of Surgical Site Infection (2017). Centre for disease control and prevention. https://www.cdc.gov/infectioncontrol/guidelines/ssi/index.html accessed 15th March 2019.
4. Simodynes, EE, Cochran, RM. Aeromonas hydrophila infection complicating an open tibial fracture. A case report. Clin OrthopRelat Res 1982; 171: 117–120
5. Levitsky KA, Hozack WJ, Balderston RA, et al. Evaluation of the painful prosthetic joint. Relative value of bone scan, sedimentation rate, and joint aspiration. J Arthroplasty. 1991;6:237–244.
6. Schinsky MF, Della Valle CJ, Sporer SM, et al. Perioperative testing for joint infection in patients undergoing revision total hip arthroplasty. J Bone Joint Surg Am. 2008;90:1869–1875. doi: 10.2106/JBJS.G.01255.
7. Spangehl MJ, Masri BA, O’Connell JX, et al. Prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am. 1999;81:672–683.
8. Bilgen O, Atici T, Durak K, et al. C-reactive protein values and erythrocyte sedimentation rates after total hip and total knee arthroplasty. J Int Med Res. 2001;29:7–12.
9. Park KK, Kim TK, Chang CB, et al. Normative temporal values of CRP and ESR in unilateral and staged bilateral TKA. Clin OrthopRelat Res. 2008;466:179–188. doi: 10.1007/s11999-007-0001-x. [PMC free article]
10. Forster IW, Crawford R. Sedimentation rate in infected and uninfected total hip arthroplasty. Clin OrthopRelat Res. 1982;168:48–52.
11. Lee Y, McKechnie T, Doumouras AG, Handler C, Eskicioglu C, Gmora S, Anvari M, Hong D. Diagnostic Value of C-Reactive Protein Levels in Postoperative Infectious Complications After Bariatric Surgery: a Systematic Review and Meta-Analysis. Obes Surg. 2019 Mar 21
12. Aljabi Y, Manca A, Ryan J, Elshawarby A. Value of procalcitonin as a marker of surgical site infection following spinal surgery. The Surgeon. 2019 Apr 1;17(2):97-101.
13. Cyteval, C, Hamm, V, Sarrabère, MP. Painful infection at the site of hip prosthesis: CT imaging. Radiology 2002; 224(2): 477–483
14. Kohan, AA, Rubbert, C, Vercher-Conejero, JL. The impact of orthopedic metal artifact reduction software on interreader variability when delineating areas of interest in the head and neck. PractRadiat Oncol 2015; 5(4): e309–e315.
15. Cyteval, C, Bourdon, A. Imaging orthopedic implant infections. Diagn Interv Imaging 2012; 93(6): 547–557
16. Plodkowski,A.J., Hayter,C.L., Miller,T.T., Nguyen,J.T., Potter,H.G. Lamellated hyperintense synovitis: potential MR imaging sign of an infected knee arthroplasty. 2013/1; 1: 256-260
17. Talbot BS, Weinberg EP. MR imaging with metal-suppression sequences for evaluation of total joint arthroplasty. Radiographics. 2015 Nov 20;36(1):209-25.
18. Glaudemans, AWJM, Signore, A. FDG-PET/CT in infections: the imaging method of choice? Eur J Nucl Med Mol Imaging 2010; 37(10): 1986–1991.
19. Basu, S, Kwee, TC, Saboury, B. FDG-PET for diagnosing infection in hip and knee prostheses: prospective study in 221 prostheses and subgroup comparison with combined (111)In-labeled leukocyte/(99)mTc-sulfur colloid bone marrow imaging in 88 prostheses. J Nucl Med 2014; 39(7): 609–615.
20. Schwotzer N, Wahl P, Fracheboud D, Gautier E, Chuard C. Optimal culture incubation time in orthopedic device-associated infections: a retrospective analysis of prolonged 14-day incubation. Journal of clinical microbiology. 2014 Jan 1;52(1):61-6.
21. Bémer, P.; Plouzeau, C.; Tande, D.; Léger, J.; Giraudeau, B.; Valentin, A.S.; Jolivet-Gougeon, A.; Vincent, P.; Corvec, S.; Gibaud, S.; et al. Evaluation of 16S rRNA gene PCR sensitivity and specificity for diagnosis of prosthetic joint infection: A prospective multicenter cross-sectional study. J. Clin. Microbiol. 2014, 52, 3583–3589.
22. Hartley, J.C.; Harris, K.A. Molecular techniques for diagnosing prosthetic joint infections. J. Antimicrob. Chemother. 2014, 69 (Suppl. 1), i21–i24.
23. Yano, M.H.; Klautau, G.B.; da Silva, C.B.; Nigro, S.; Avanzi, O.; Mercadante, M.T.; Salles, M.J.C. Improved diagnosis of infection associated with osteosynthesis by use of sonication of fracture fixation implants. J. Clin. Microbiol. 2014, 52, 4176–4182.
24. Yano, M.H.; Klautau, G.B.; da Silva, C.B.; Nigro, S.; Avanzi, O.; Mercadante, M.T.; Salles, M.J.C. Improved diagnosis of infection associated with osteosynthesis by use of sonication of fracture fixation implants. J. Clin. Microbiol. 2014, 52, 4176–4182.
25. Schinsky, M.F.; Della Valle, C.J.; Sporer, S.M.; Paprosky, W.G. Perioperative testing for joint infection in patients undergoing revision total hip arthroplasty. J. Bone Jt. Surg. Ser. A 2008, 90, 1869–1875.
26. Drago, L.; Signori, V.; De Vecchi, E.; Vassena, C.; Palazzi, E.; Cappelletti, L.; Romanò, D.; Romanò, C.L. Use of dithiothreitol to improve the diagnosis of prosthetic joint infections. J. Orthop. Res. 2013, 31, 1694–1699.
27. Al-Adsani A., Niazy M. N. ,Mohd M., Ewing’s sarcoma of the ilium mimicking sacroiliitis Rheumatology (1999) 38 (8): 792-793
28. Wang J, Wu X, Xi ZJ. Langerhans cell histiocytosis of bone in children: a clinicopathologic study of 108 cases. World J Pediatr. 2010 Aug;6(3):255-9.


How to Cite this article: Kothari M. Diagnosis of surgical site infection. Journal of Clinical Orthopaedics July-Dec 2019;4(2):12-16.

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