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Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

Journal of Clinical Orthopaedics | Vol 9 | Issue 2 | July-December 2024 | page: 114-117 | Swati Lalchandani, Rajesh Yadav, Rakesh Parmar, Rajesh Lalchandani, Shashikant Prakash DOI: https://doi.org/10.13107/jcorth.2024.v09i02.688 Submitted Date: 15 Jul 2024, Review Date: 10 Aug 2024, Accepted Date: 05 Oct 2024 & Published Date: 10 December 2024 Author: Swati Lalchandani [1], Rajesh […]

Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

Journal of Clinical Orthopaedics | Vol 9 | Issue 2 | July-December 2024 | page: 109-113 | Damini Shah, Prasad Bhagunde, Nihar Modi DOI: https://doi.org/10.13107/jcorth.2024.v09i02.686 Submitted Date: 14 Aug 2024, Review Date: 27 Aug 2024, Accepted Date: 14 Oct 2024 & Published Date: 10 Dec 2024 Author: Damini Shah [1], Prasad Bhagunde [2, 3, 4, […]

Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

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Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

DOI: https://doi.org/10.13107/jcorth.2024.v09i02.688

Submitted Date: 15 Jul 2024, Review Date: 10 Aug 2024, Accepted Date: 05 Oct 2024 & Published Date: 10 December 2024

Author: Swati Lalchandani [1], Rajesh Yadav [2], Rakesh Parmar [2], Rajesh Lalchandani [2], Shashikant Prakash [2]

[1] Department of Microbiology, New Delhi Pathology Clinic, New Delhi, India.
[2] Department of Orthopaedics, ESIPGIMSR, New Delhi, India.

Address of Correspondence

Dr. Rakesh Parmar,
Senior Resident, Department of Orthopaedics, ESIPGIMSR, New Delhi, India.
E-mail: rksdoc@gmail.com

Abstract

Objectives: The objectives of this study were to assess the need for antibiotic prophylaxis in soft-tissue surgeries of short duration without usage of implant in the field of orthopedics.
Methods: A prospective and comparative randomized study was performed on 100 cases with clean elective surgical procedure of short duration <⅟2 h. Data were analyzed for development of surgical site infection (SSI) in clean elective soft-tissue procedures of short duration.
Results: In our carefully selected cohort of patients of clean soft-tissue surgeries of less than half hour duration without involving the use of implant, two groups were made based on block randomization technique, one of which got a shot of pre-operative antibiotic prophylaxis and other did not. Mean patient age was 36.1 years (04 month-66 years). In both groups at all age levels, no infection was found. In the group which received antibiotic 80.8% were female and 19.2% were male, and in the antibiotic not given group had 61.5% female and 38.5% male. Therefore, it is evident that antibiotics did not provide clinical or statistical protection against SSI in clean elective soft-tissue procedures of short duration.
Conclusion: We suggest stratification of use of antibiotic prophylaxis, that is, antibiotic prophylaxis is required for surgeries of longer duration involving placement of implants but not required in surgeries of short duration which do not involve placement of implants in the field of orthopedics.
Keywords: Surgical Prophylaxis, Surgical site infection, Orthopaedics Practice

References

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How to Cite this article: Lalchandani S, Yadav R, Parmar R, Lalchandani R, Prakash S. Surgical Prophylaxis: Is it Always Needed in Orthopaedics Practice. Journal of Clinical Orthopaedics Jul-dec 2024;9(2):114-117.

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Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

December 10, 2024/in Vol 9 | Issue 2 | July - Dec 2024 /by editor.jcorth

DOI: https://doi.org/10.13107/jcorth.2024.v09i02.686

Submitted Date: 14 Aug 2024, Review Date: 27 Aug 2024, Accepted Date: 14 Oct 2024 & Published Date: 10 Dec 2024

Author: Damini Shah [1], Prasad Bhagunde [2, 3, 4, 5], Nihar Modi [2, 4, 6]

[1] Novo Tissue Bank and Research Centre, Mumbai, Maharashtra, India.
[2] Department of Orthopaedics, Sona Medical Centre, Mumbai, Maharashtra, India.
[3] Department of Orthopaedics, Saifee Hospital, Mumbai, Maharashtra, India.
[4] Department of Orthopaedics, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
[5] Department of Orthopaedics, Breach Candy Hospital Trust, Mumbai, Maharashtra, India.
[6] Department of Orthopaedics, Criticare Asia Multispeciality Hospital and Research Centre, Mumbai, Maharashtra, India.

Address of Correspondence

Dr. Damini Shah,
Assistant Director of Operations, Novo Tissue Bank and Research Centre, Mumbai, Maharashtra, India.
E-mail: daminirshah@gmail.com

Abstract

Musculoskeletal tissue donation from deceased donors plays a crucial role in advancing orthopedic and reconstructive surgeries, providing an alternative to autografts and synthetic implants. Despite its clinical significance, the adoption of tissue donation in India remains limited due to challenges such as low public awareness, cultural barriers, and infrastructural constraints. This study analyzes 16 cases of musculoskeletal tissue retrieval conducted in Mumbai between 2022 and 2023, highlighting procedural protocols, ethical considerations, and logistical challenges. The analysis underscores the importance of timely retrieval, adherence to regulatory frameworks like the Transplantation of Human Organs and Tissues Act (THOTA) 1994, and stringent quality assurance measures to ensure the safety and efficacy of allografts. Results demonstrate a high success rate, with over 98% of retrieved tissues meeting bioburden and structural integrity standards. The paper advocates for standardized protocols, improved public awareness, and enhanced training for healthcare professionals to advance tissue donation practices in India. This effort is pivotal for addressing unmet medical needs and fostering a compassionate healthcare system.
Keywords: Allografts, Musculoskeletal tissue donation, Tissue Banking, Orthobiologics, Reconstructive surgeries

References

1. India orthopedic procedures count by segments and forecast to 2030. (2024, June 14). Market Research Reports & Consulting | GlobalData UK Ltd.
2. (2011) The Transplantation of Human Organs and Tissues Act, 1994. Gazette of India, Ext., Pt. II, S. 1.
3. Guidelines for Tissue Banking (2021) rottosottokem.in. Available at: https://rottosottokem.in/downloads/SOTTO%20Tissue%20Guidelines.pdf.
4. Morales Pedraza, J., Lobo Gajiwala, A. and Martinez Pardo, M.E. (2010) ‘A review of the International Atomic Energy Agency (IAEA) international standards for tissue banks’, Cell and Tissue Banking, 13(1), pp. 15–25. doi:10.1007/s10561-010-9215-3.
5. Nather, A. et al. (2018) ‘Tissue banking in Asia Pacific region: Past, present and future’, Cell and Tissue Banking, 19(2), pp. 229–240. doi:10.1007/s10561-018-9697-y.
6. Yusof, N., Shamsudin, A. R., Mohamad, H., Hassan, A., Yong, A. C., & Rahman, M. N. F. A. (2005). BIOBURDEN ESTIMATION IN RELATION TO TISSUE PRODUCT QUALITY AND RADIATION DOSE VALIDATION. In Elsevier eBooks. https://doi.org/10.1533/9781845690779.5.319

How to Cite this article: Shah D, Bhagunde P, Modi N. Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges. Journal of Clinical Orthopaedics July-December 2024;9(2):109-113.

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Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

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Surgical Prophylaxis: Is it Always Needed in Orthopedics Practice

Author: Swati Lalchandani [1], Rajesh Yadav [2], Rakesh Parmar [2], Rajesh Lalchandani [2], Shashikant Prakash [2]

Abstract

References

Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges

Author: Damini Shah [1], Prasad Bhagunde [2, 3, 4, 5], Nihar Modi [2, 4, 6]

Abstract

References

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