Dr. Damini Shah,
Assistant Director of Operations, Novo Tissue Bank and Research Centre, Mumbai, Maharashtra, India.
E-mail: daminirshah@gmail.com
Musculoskeletal tissue donation from deceased donors plays a crucial role in advancing orthopedic and reconstructive surgeries, providing an alternative to autografts and synthetic implants. Despite its clinical significance, the adoption of tissue donation in India remains limited due to challenges such as low public awareness, cultural barriers, and infrastructural constraints. This study analyzes 16 cases of musculoskeletal tissue retrieval conducted in Mumbai between 2022 and 2023, highlighting procedural protocols, ethical considerations, and logistical challenges. The analysis underscores the importance of timely retrieval, adherence to regulatory frameworks like the Transplantation of Human Organs and Tissues Act (THOTA) 1994, and stringent quality assurance measures to ensure the safety and efficacy of allografts. Results demonstrate a high success rate, with over 98% of retrieved tissues meeting bioburden and structural integrity standards. The paper advocates for standardized protocols, improved public awareness, and enhanced training for healthcare professionals to advance tissue donation practices in India. This effort is pivotal for addressing unmet medical needs and fostering a compassionate healthcare system.
Keywords: Allografts, Musculoskeletal tissue donation, Tissue Banking, Orthobiologics, Reconstructive surgeries
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