Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges
Journal of Clinical Orthopaedics | Vol 9 | Issue 2 | July-December 2024 | page: 109-113 | Damini Shah, Prasad Bhagunde, Nihar Modi
DOI: https://doi.org/10.13107/jcorth.2024.v09i02.686
Submitted Date: 14 Aug 2024, Review Date: 27 Aug 2024, Accepted Date: 14 Oct 2024 & Published Date: 10 Dec 2024
Author: Damini Shah [1], Prasad Bhagunde [2, 3, 4, 5], Nihar Modi [2, 4, 6]
[1] Novo Tissue Bank and Research Centre, Mumbai, Maharashtra, India.
[2] Department of Orthopaedics, Sona Medical Centre, Mumbai, Maharashtra, India.
[3] Department of Orthopaedics, Saifee Hospital, Mumbai, Maharashtra, India.
[4] Department of Orthopaedics, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
[5] Department of Orthopaedics, Breach Candy Hospital Trust, Mumbai, Maharashtra, India.
[6] Department of Orthopaedics, Criticare Asia Multispeciality Hospital and Research Centre, Mumbai, Maharashtra, India.
Address of Correspondence
Dr. Damini Shah,
Assistant Director of Operations, Novo Tissue Bank and Research Centre, Mumbai, Maharashtra, India.
E-mail: daminirshah@gmail.com
Abstract
Musculoskeletal tissue donation from deceased donors plays a crucial role in advancing orthopedic and reconstructive surgeries, providing an alternative to autografts and synthetic implants. Despite its clinical significance, the adoption of tissue donation in India remains limited due to challenges such as low public awareness, cultural barriers, and infrastructural constraints. This study analyzes 16 cases of musculoskeletal tissue retrieval conducted in Mumbai between 2022 and 2023, highlighting procedural protocols, ethical considerations, and logistical challenges. The analysis underscores the importance of timely retrieval, adherence to regulatory frameworks like the Transplantation of Human Organs and Tissues Act (THOTA) 1994, and stringent quality assurance measures to ensure the safety and efficacy of allografts. Results demonstrate a high success rate, with over 98% of retrieved tissues meeting bioburden and structural integrity standards. The paper advocates for standardized protocols, improved public awareness, and enhanced training for healthcare professionals to advance tissue donation practices in India. This effort is pivotal for addressing unmet medical needs and fostering a compassionate healthcare system.
Keywords: Allografts, Musculoskeletal tissue donation, Tissue Banking, Orthobiologics, Reconstructive surgeries
References
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3. Guidelines for Tissue Banking (2021) rottosottokem.in. Available at: https://rottosottokem.in/downloads/SOTTO%20Tissue%20Guidelines.pdf.
4. Morales Pedraza, J., Lobo Gajiwala, A. and Martinez Pardo, M.E. (2010) ‘A review of the International Atomic Energy Agency (IAEA) international standards for tissue banks’, Cell and Tissue Banking, 13(1), pp. 15–25. doi:10.1007/s10561-010-9215-3.
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| How to Cite this article: Shah D, Bhagunde P, Modi N. Musculoskeletal Tissue Retrieval from Deceased Donors in India: Protocols and Challenges. Journal of Clinical Orthopaedics July-December 2024;9(2):109-113. |
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