Late Infection in Scoliosis: A Meta-Analysis
Review Article | Journal of Clinical Orthopaedics | Vol 10 | Issue 2 | July-December 2025 | page: 61-69 | Vishal Kumar, Manuj Jain, Aditya Gupta, Arvind Vatkar, Deepshikha, Sarvdeep Singh Dhatt, Sachin Kale
DOI: https://doi.org/10.13107/jcorth.2025.v10.i02.778
Open Access License: CC BY-NC 4.0
Copyright Statement: Copyright © 2025; The Author(s).
Submitted Date: 02 Oct 2025, Review Date: 20 Oct 2025, Accepted Date: 23 Nov 2025 & Published Date: 10 Dec 2025
Author: Vishal Kumar [1], Manuj Jain [4], Aditya Gupta [1], Arvind Vatkar [2], Deepshikha [3], Sarvdeep Singh Dhatt [1], Sachin Kale [5]
[1] Department of Orthopaedics, Postgraduate Institute of Medical Education and Research, Chandigarh, India,
[2] Department of Orthopaedics, Base Hospital, Bagdogra, West Bengal, Department of Orthopaedics,
[3] MGM Medical College, Mumbai, Maharashtra, India,
[4] Department of Physical Medicine and Rehabilitation, Postgraduate Institute of Medical Education and Research, Chandigarh, India,
[5] Department of Orthopaedics, Dr D Y Patil School of Medicine, Mumbai, Maharashtra, India.
Address of Correspondence
Dr. Vishal Kumar,
Department of Orthopaedics, Postgraduate Institute of Medical Education and Research, Chandigarh, India,
E-mail: drkumarvishal@gmail.com
Abstract
This meta-analysis aims to evaluate the incidence, risk factors, and clinical outcomes of late infections in scoliosis patients following spinal instrumentation. A systematic review of studies indexed in PubMed, Embase, and Scopus databases was conducted. Studies that focused on scoliosis patients with late-developing infections, particularly after surgical treatment involving spinal instrumentation, were included. Data on infection rates, risk factors such as patient age and comorbidities, surgical techniques, and clinical outcomes were extracted and analyzed. Statistical methods, including pooled incidence rates and subgroup analysis, were used to assess the significance of the findings. The incidence of late infections varied significantly across different scoliosis types, with idiopathic scoliosis showing lower infection rates compared to neuromuscular scoliosis. Key risk factors identified included the duration of surgery, the use of prophylactic antibiotics, and patient comorbidities, particularly obesity. Late infections were often associated with a higher rate of reoperations, hardware removal, and prolonged antibiotic therapy. Late infections following spinal instrumentation in scoliosis patients remain a significant concern, with certain patient populations at higher risk. Early detection and preventive strategies are essential to mitigate these risks and improve clinical outcomes. Future research should focus on standardizing infection prevention protocols and long-term monitoring of scoliosis patients post-surgery.
Keywords: Late infection, scoliosis, spinal instrumentation, meta-analysis, risk factors, post-operative complications, neuromuscular scoliosis, idiopathic scoliosis.
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| How to Cite this Article: Kumar V, Jain M, Gupta A, Vatkar A, Deepshikha, Dhatt SS, Kale S. Late Infection in Scoliosis: A Meta-Analysis. Journal of Clinical Orthopaedics. July-December 2025;10(2):61-69. |
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